HIV/AIDS Topics AIDS 2010: Oral Tenofovir for Pre-exposure Prophylaxis Appears Safe and Does Not Discourage Safer Sex
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- Category: HIV Prevention
- Published on Friday, 30 July 2010 13:56
- Written by Liz Highleyman
HIV pre-exposure prophylaxis (PrEP) using once-daily oral tenofovir appeared safe and did not increase the likelihood of risky sexual behavior among men who have sex with men in 3 U.S. cities, researchers reported in a late-breaker presentation at the XVIII International Conference on AIDS (AIDS 2010) last week in Vienna. The study found no indication of significant safety issues including kidney problems or bone loss. None of the 7 men who became HIV infected during the 2-year follow-up period were taking tenofovir, but this analysis was not powered to determine effectiveness.
AIDS 2010: Early Antiretroviral Treatment Reduces New HIV Infections, Says British Columbia Study
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- Category: Treatment as Prevention
- Published on Friday, 23 July 2010 13:56
- Written by HIVandHepatitis.com
A study published in the July 18, 2010 advance online edition of the Lancet (free full text with registration) and discussed at the XVIII International AIDS Conference (AIDS 2010) this week in Vienna offers further evidence that widespread early antiretroviral therapy (ART) can reduce the spread of HIV at a population level. Universal early ART is not without controversy, however, due to concerns about side effects, drug resistance, and resource allocation.
Experts Call for 'New Era' of Unified HIV Vaccine Research
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- Category: HIV Vaccines
- Published on Monday, 19 July 2010 17:11
- Written by Press Release
HIV vaccine researchers, public health officials, advocates, and funders came together at the XVIII International AIDS Conference (AIDS 2010) on Monday, July 19, to review recent progress in vaccine development and call for a "new era" of rapid exploration of promising approaches with increased collaboration and funding. Many obstacles remain, speakers acknowledged, but the field also has some encouraging recent leads, including findings from a Thai trial that showed the first-ever -- albeit modest -- evidence that a vaccine can reduce the risk of HIV infection in humans.
CAPRISA Microbicide Trial Shows Tenofovir Vaginal Gel Reduces HIV Transmission Risk by 39%
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- Category: HIV Prevention
- Published on Tuesday, 20 July 2010 13:56
- Written by Liz Highleyman
An antiretroviral vaginal gel containing tenofovir offered women moderate protection against HIV infection when administered before and after sex, according to findings from the CAPRISA 004 trial published in the July 19, 2010 issue of Science and announced at the XVIII International AIDS Conference (AIDS 2010).
Researchers Discover Broadly Neutralizing Antibodies that Act Against 91% of HIV Strains
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- Category: HIV Vaccines
- Published on Tuesday, 13 July 2010 14:17
- Written by NIAID
Researchers with the National Institute of Allergy and Infectious Diseases (NIAID) Vaccine Research Center have identified 2 new antibodies, dubbed VRC01 and VRC02, that can neutralize more than 90% of know HIV strains, according to reports in the July 8, 2010 advance online edition of Science. These antibodies -- which target a conserved (mutation-resistant) part of the HIV gp120 envelope protein that attaches to the CD4 surface receptor to enter cells -- could potentially be used to create a future preventive vaccine, protective microbicide, or therapeutic vaccine to slow disease progression in people already infected.
More Articles...
- Scientists at the U.S. National Institutes of Health Discover Human Antibodies That Can Stop Most HIV Strains from Infecting Human Cells
- Global Experts Call for Better Match between HIV Prevention Efforts and Groups at Greatest Risk
- Antiretroviral Therapy Reduces Heterosexual HIV Transmission Risk by More than 90%
- Antiretroviral Therapy for HIV Prevention Could Lead to Drug Resistance If Not Carefully Implemented
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