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Universal Testing and Treatment Could Reduce New HIV Infections by 76%

New HIV infections among gay men could decrease by 59% if all HIV positive adults now in care start antiretroviral therapy, and the number could drop further with universal annual testing, according to recently published mathematical models.

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Genital Viral Load Predicts Heterosexual HIV Transmission Risk

Higher levels of HIV RNA in semen or female genital fluids are associated with a greater likelihood of HIV transmission during sex.

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Vaccine Used in STEP Trial Alters HIV Genes

The adenovirus vaccine candidate used in the STEP trial did not significantly reduce HIV infection, but did alter the genetic makeup of the virus, according to a recent report in Nature Medicine. alt

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HIV Envelope Discovery Could Reveal New Vaccine Targets

Researchers have identified how the HIV envelope changes shape after binding to a host cell, exposing conserved proteins that might be good targets for a vaccine.

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CROI 2011: Researchers Report Further Findings from iPrEx PrEP Trial

Investigators presented further details of findings from the ground-breaking iPrEx trial this week at the 18th Conference on Retroviruses and Opportunistic Infections (CROI 2011) in Boston. With longer follow-up, pre-exposure prophylaxis (PrEP) using tenofovir/emtricitabine (Truvada) continued to have a protective effect against HIV acquisition, but signs of mild bone loss raise potential concerns about safety.

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