HIV/AIDS Topics How Much Can Early Treatment Reduce HIV Transmission Among Discordant Couples?
- Details
- Category: HIV Prevention
- Published on Tuesday, 01 November 2011 00:00
- Written by Liz Highleyman
Treating the HIV positive partner in serodiscordant couples can decrease the risk of transmitting the virus, but the extent of the reduction will likely vary from country to country based on population size, HIV prevalence, and number of discordant couples, according to a mathematical model study described in the October 11, 2011, advance online edition of AIDS.
Tenofovir Microbicide Gel May Prevent Genital Herpes in Addition to HIV Infection
- Details
- Category: Microbicides
- Published on Tuesday, 25 October 2011 00:00
- Written by NIH
A vaginal gel containing the HIV nucleotide reverse transcriptase inhibitor tenofovir (known as Viread in pill form, also in the Truvada and Atripla coformulations) inhibits replication of herpes simplex virus, researchers reported in the October 4, 2011, issue of Cell Host and Microbes. Tenofovir gel has already been shown to reduce HIV infection by about 40%, and the new findings suggest it may have a dual benefit.
Hormonal Contraception Increases Risk of HIV Infection for Women and Men
- Details
- Category: HIV Prevention
- Published on Tuesday, 04 October 2011 00:00
- Written by Liz Highleyman
Use of hormonal contraceptives, especially the injectable progesterone Depot Provera, was associated with nearly double the risk of acquiring HIV for both women and their male partners in a large African trial. While the absolute increase in new infections was small, these findings raise important questions about the underlying biological mechanisms, and may shed light on some of the puzzling outcomes of recent HIV prevention studies.
California Governor Signs Syringe Purchase and Needle Exchange Bills
- Details
- Category: Injection Drug Use
- Published on Thursday, 13 October 2011 00:00
- Written by Drug Policy Alliance
California Governor Jerry Brown last week signed 2 harm reduction bills intended to decrease the transmission of blood-borne infections such as HIV and hepatitis B and C among injection drug users. One bill will permit pharmacies to sell new syringes without a prescription, while the other will enable the state Department of Public Health to authorize new syringe exchange programs in consultation with local public health authorities.
Women's HIV Prevention Trial Halts Oral Tenofovir Arm
- Details
- Category: HIV Prevention
- Published on Friday, 30 September 2011 00:00
- Written by Liz Highleyman
Researchers will discontinue one arm of the VOICE study testing oral tenofovir (Viread) pills after an interim analysis by an independent monitoring board showed that the trial would be unlikely to show that the drug works better than placebo for pre-exposure prophylaxis (PrEP) to prevent HIV infection. Other study arms testing the tenofovir/emtricitabine combination pill (Truvada) and a tenofovir vaginal gel will continue. No safety concerns were identified.
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